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karius test pathogen categories  (Karius Inc)

 
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    Structured Review

    Karius Inc karius test pathogen categories
    Flow diagram depicting patient and sample selection for the comparison of BAL fluid mcfDNA sequencing with the <t>Karius®</t> <t>test</t> and standard of care testing.
    Karius Test Pathogen Categories, supplied by Karius Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/karius test pathogen categories/product/Karius Inc
    Average 86 stars, based on 1 article reviews
    karius test pathogen categories - by Bioz Stars, 2026-05
    86/100 stars

    Images

    1) Product Images from "Microbial cell-free DNA sequencing of bronchoalveolar lavage fluid improves diagnostic yield and may add clinical utility in immunocompromised patients with severe pneumonia"

    Article Title: Microbial cell-free DNA sequencing of bronchoalveolar lavage fluid improves diagnostic yield and may add clinical utility in immunocompromised patients with severe pneumonia

    Journal: medRxiv

    doi: 10.1101/2025.11.05.25339543

    Flow diagram depicting patient and sample selection for the comparison of BAL fluid mcfDNA sequencing with the Karius® test and standard of care testing.
    Figure Legend Snippet: Flow diagram depicting patient and sample selection for the comparison of BAL fluid mcfDNA sequencing with the Karius® test and standard of care testing.

    Techniques Used: Selection, Comparison, Sequencing

    Additive diagnostic value of BAL fluid mcfDNA sequencing with the Karius® test (KT-BAL) compared to standard of care (SOC) testing in immunocompromised patients with pneumonia. A) Number of organisms across all samples identified by either SOC alone, KT-BAL alone, or both techniques, split by KT-BAL category. B) Organisms identified exclusively by KT-BAL across all samples, split by KT-BAL category.
    Figure Legend Snippet: Additive diagnostic value of BAL fluid mcfDNA sequencing with the Karius® test (KT-BAL) compared to standard of care (SOC) testing in immunocompromised patients with pneumonia. A) Number of organisms across all samples identified by either SOC alone, KT-BAL alone, or both techniques, split by KT-BAL category. B) Organisms identified exclusively by KT-BAL across all samples, split by KT-BAL category.

    Techniques Used: Diagnostic Assay, Sequencing

    Analysis of microbial read and human read values reported by the BAL fluid Karius® test (KT-BAL). A) Organisms that are identified in at least five samples by both KT-BAL and standard of care (SOC) testing and in at least five other samples by only KT-BAL have significantly lower microbial read values in the SOC + KT-BAL samples (Mann-Whitney U test, FDR < 0.05). B) KT-BAL microbial read values strongly correlate with culture quantities from SOC (Spearman’s rank correlation). C) KT-BAL human read values do not correlate with markers of host immune response (Spearman’s rank correlation).
    Figure Legend Snippet: Analysis of microbial read and human read values reported by the BAL fluid Karius® test (KT-BAL). A) Organisms that are identified in at least five samples by both KT-BAL and standard of care (SOC) testing and in at least five other samples by only KT-BAL have significantly lower microbial read values in the SOC + KT-BAL samples (Mann-Whitney U test, FDR < 0.05). B) KT-BAL microbial read values strongly correlate with culture quantities from SOC (Spearman’s rank correlation). C) KT-BAL human read values do not correlate with markers of host immune response (Spearman’s rank correlation).

    Techniques Used: MANN-WHITNEY

    Patients for whom BAL fluid mcfDNA testing with the Karius® test (KT-BAL) identified Category One or Two organisms missed by standard of care (SOC) had significantly more cumulative intubation days compared to patients where KT-BAL and SOC were concordant for all Category One or Two organisms. Hospital length of stay, ICU length of stay, and ICU mortality were worse in the KT-BAL only group, but these differences were not significant (Mann-Whitney U test for continuous variables, Fisher’s exact test for mortality).
    Figure Legend Snippet: Patients for whom BAL fluid mcfDNA testing with the Karius® test (KT-BAL) identified Category One or Two organisms missed by standard of care (SOC) had significantly more cumulative intubation days compared to patients where KT-BAL and SOC were concordant for all Category One or Two organisms. Hospital length of stay, ICU length of stay, and ICU mortality were worse in the KT-BAL only group, but these differences were not significant (Mann-Whitney U test for continuous variables, Fisher’s exact test for mortality).

    Techniques Used: MANN-WHITNEY



    Similar Products

    karius test pathogen categories  (Karius Inc)
    86
    Karius Inc karius test pathogen categories
    Flow diagram depicting patient and sample selection for the comparison of BAL fluid mcfDNA sequencing with the <t>Karius®</t> <t>test</t> and standard of care testing.
    Karius Test Pathogen Categories, supplied by Karius Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/karius test pathogen categories/product/Karius Inc
    Average 86 stars, based on 1 article reviews
    karius test pathogen categories - by Bioz Stars, 2026-05
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    Flow diagram depicting patient and sample selection for the comparison of BAL fluid mcfDNA sequencing with the Karius® test and standard of care testing.

    Journal: medRxiv

    Article Title: Microbial cell-free DNA sequencing of bronchoalveolar lavage fluid improves diagnostic yield and may add clinical utility in immunocompromised patients with severe pneumonia

    doi: 10.1101/2025.11.05.25339543

    Figure Lengend Snippet: Flow diagram depicting patient and sample selection for the comparison of BAL fluid mcfDNA sequencing with the Karius® test and standard of care testing.

    Article Snippet: Karius® Test Pathogen Categories: The operating characteristics of the Karius® BAL test have recently been submitted for publication.

    Techniques: Selection, Comparison, Sequencing

    Additive diagnostic value of BAL fluid mcfDNA sequencing with the Karius® test (KT-BAL) compared to standard of care (SOC) testing in immunocompromised patients with pneumonia. A) Number of organisms across all samples identified by either SOC alone, KT-BAL alone, or both techniques, split by KT-BAL category. B) Organisms identified exclusively by KT-BAL across all samples, split by KT-BAL category.

    Journal: medRxiv

    Article Title: Microbial cell-free DNA sequencing of bronchoalveolar lavage fluid improves diagnostic yield and may add clinical utility in immunocompromised patients with severe pneumonia

    doi: 10.1101/2025.11.05.25339543

    Figure Lengend Snippet: Additive diagnostic value of BAL fluid mcfDNA sequencing with the Karius® test (KT-BAL) compared to standard of care (SOC) testing in immunocompromised patients with pneumonia. A) Number of organisms across all samples identified by either SOC alone, KT-BAL alone, or both techniques, split by KT-BAL category. B) Organisms identified exclusively by KT-BAL across all samples, split by KT-BAL category.

    Article Snippet: Karius® Test Pathogen Categories: The operating characteristics of the Karius® BAL test have recently been submitted for publication.

    Techniques: Diagnostic Assay, Sequencing

    Analysis of microbial read and human read values reported by the BAL fluid Karius® test (KT-BAL). A) Organisms that are identified in at least five samples by both KT-BAL and standard of care (SOC) testing and in at least five other samples by only KT-BAL have significantly lower microbial read values in the SOC + KT-BAL samples (Mann-Whitney U test, FDR < 0.05). B) KT-BAL microbial read values strongly correlate with culture quantities from SOC (Spearman’s rank correlation). C) KT-BAL human read values do not correlate with markers of host immune response (Spearman’s rank correlation).

    Journal: medRxiv

    Article Title: Microbial cell-free DNA sequencing of bronchoalveolar lavage fluid improves diagnostic yield and may add clinical utility in immunocompromised patients with severe pneumonia

    doi: 10.1101/2025.11.05.25339543

    Figure Lengend Snippet: Analysis of microbial read and human read values reported by the BAL fluid Karius® test (KT-BAL). A) Organisms that are identified in at least five samples by both KT-BAL and standard of care (SOC) testing and in at least five other samples by only KT-BAL have significantly lower microbial read values in the SOC + KT-BAL samples (Mann-Whitney U test, FDR < 0.05). B) KT-BAL microbial read values strongly correlate with culture quantities from SOC (Spearman’s rank correlation). C) KT-BAL human read values do not correlate with markers of host immune response (Spearman’s rank correlation).

    Article Snippet: Karius® Test Pathogen Categories: The operating characteristics of the Karius® BAL test have recently been submitted for publication.

    Techniques: MANN-WHITNEY

    Patients for whom BAL fluid mcfDNA testing with the Karius® test (KT-BAL) identified Category One or Two organisms missed by standard of care (SOC) had significantly more cumulative intubation days compared to patients where KT-BAL and SOC were concordant for all Category One or Two organisms. Hospital length of stay, ICU length of stay, and ICU mortality were worse in the KT-BAL only group, but these differences were not significant (Mann-Whitney U test for continuous variables, Fisher’s exact test for mortality).

    Journal: medRxiv

    Article Title: Microbial cell-free DNA sequencing of bronchoalveolar lavage fluid improves diagnostic yield and may add clinical utility in immunocompromised patients with severe pneumonia

    doi: 10.1101/2025.11.05.25339543

    Figure Lengend Snippet: Patients for whom BAL fluid mcfDNA testing with the Karius® test (KT-BAL) identified Category One or Two organisms missed by standard of care (SOC) had significantly more cumulative intubation days compared to patients where KT-BAL and SOC were concordant for all Category One or Two organisms. Hospital length of stay, ICU length of stay, and ICU mortality were worse in the KT-BAL only group, but these differences were not significant (Mann-Whitney U test for continuous variables, Fisher’s exact test for mortality).

    Article Snippet: Karius® Test Pathogen Categories: The operating characteristics of the Karius® BAL test have recently been submitted for publication.

    Techniques: MANN-WHITNEY